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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12150 | N-Methylbenzamide | PDE | |
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity. | |||
T24656 | PQ-10 | A844337,PQ 10,A-844337,A 844337 | PDE |
PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker. | |||
T16499 | Mardepodect | PF-2545920 | PDE |
Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE. It is potentially useful for the treatment of schizophrenia. Phosphodie... | |||
T28969 | THPP-4 | ||
THPP-4 inhibits phosphodiesterase 10A (PDE10A). | |||
T27684 | JNJ-42259152 | JNJ42259152,JNJ 42259152 | |
JNJ-42259152 is a phosphodiesterase 10A PET tracer. | |||
T28968 | THPP-2 | ||
HPP-2 is a novel phosphodiesterase 10A (PDE10A) inhibitor used to treat schizophrenia. | |||
T32307 | JNJ-42259152 F-18 | ||
JNJ-42259152 F-18 can be used as a Novel Phosphodiesterase 10A PET Tracer. | |||
T70761 | ASP9436 Dihydrochloride | ||
ASP9436 Dihydrochloride is a potent, selective and orally active phosphodiesterase 10A inhibitor. | |||
T23722 | AMG-7980 | AMG7980 | |
AMG-7980 is a highly specific phosphodiesterase 10A ligand. It shows a good uptake in the striatum. | |||
T12119 | MT-3014 | Others | |
MT-3014 is a potent, highly selective and brain-penetrated inhibitor of phosphodiesterase 10A (PDE 10A)(human PDE 10A and bovine PDE 10A with IC50s of 0.062 nM and 0.09 nM , respectively). | |||
T70822 | Gemlapodect | RO554965 | |
Gemlapodect (RO554965), a phosphodiesterase 10A (PDE10A) inhibitor, is utilized in schizophrenia research. | |||
T73462 | MK-8189 | ||
MK-8189 is a potent, orally active, and selective inhibitor of Phosphodiesterase 10A (PDE10A), exhibiting a K i value of 29 pM. It has potential applications in the research of schizophrenia. |